FGL Peptide (10mg Research Vial)
Analytical Standards & Laboratory Handling
Verified laboratory protocols, reconstitution parameters, and handling guidelines.
Pharmacological Profile & Mechanism of Action
What it is: FGL is a 15-amino-acid synthetic peptide derived from the second F3 module of Neural Cell Adhesion Molecule (NCAM), engineered to activate FGFR-1 receptors in the absence of full NCAM proteins.
How it works: FGL binds FGFR-1, triggering intracellular phosphorylation cascades (ERK1/2 and CREB) that drive neuritogenesis, dendritic spine maturation, synaptogenesis, and long-term potentiation (LTP) in hippocampal neuronal networks.
Why researchers study it: Researched in cognitive enhancement, ischemic stroke recovery, and models of age-associated memory impairment.




