Coluracetam (20mg Research Vial)
Analytical Standards & Laboratory Handling
Verified laboratory protocols, reconstitution parameters, and handling guidelines.
Pharmacological Profile & Mechanism of Action
What it is: Coluracetam (MKC-231) is a synthetic racetam-class compound distinguished by its unique ability to upregulate the high-affinity choline uptake (HACU) system in cholinergic nerve terminals.
How it works: By accelerating rate-limiting choline uptake into presynaptic neurons, Coluracetam boosts acetylcholine synthesis even in neurons with depleted cholinergic function, enhancing hippocampal memory encoding and visual chromatic perception.
Why researchers study it: Evaluated in Phase 2 clinical trials for major depressive disorder comorbid with generalized anxiety and models of cholinergic cognitive decline.




