Tesamorelin
Analytical Standards & Laboratory Handling
Verified laboratory protocols, reconstitution parameters, and handling guidelines.
Pharmacological Profile & Mechanism of Action
What it is: Tesamorelin is a synthetic 44-amino-acid peptide analogue of Growth Hormone-Releasing Hormone (GHRH), modified with a trans-3-hexenoic acid moiety at its N-terminus for enhanced metabolic stability.
How it works: It acts on the pituitary gland to stimulate natural, pulsatile growth hormone release with remarkable potency. Uniquely among GHRH analogues, Tesamorelin specifically targets and reduces deep visceral adipose tissue (the dangerous fat packed around internal organs like the liver, heart, and intestines).
Why researchers study it: Studied for visceral belly fat reduction, non-alcoholic fatty liver disease (NAFLD), improving cardiovascular risk markers, and enhancing cognitive function in aging subjects.
