Follistatin-344 (1mg Research Vial)
Analytical Standards & Laboratory Handling
Verified laboratory protocols, reconstitution parameters, and handling guidelines.
Pharmacological Profile & Mechanism of Action
What it is: Follistatin-344 is an autocrine glycoprotein that binds with exceptionally high affinity to myostatin (GDF-8), activin-A, and other TGF-beta superfamily ligands, acting as an extracellular neutralizer.
How it works: By binding and sequestering myostatin before it can engage ActRIIB receptors, Follistatin lifts the physiological brake on skeletal muscle protein synthesis, triggering robust satellite cell proliferation and muscle mass accretion.
Why researchers study it: Extensively researched in gene therapy and peptide assays for severe muscular dystrophy, sarcopenia, and muscle wasting conditions.




