Pemvidutide (10mg Research Vial)
Analytical Standards & Laboratory Handling
Verified laboratory protocols, reconstitution parameters, and handling guidelines.
Pharmacological Profile & Mechanism of Action
What it is: Pemvidutide (ALT-801) is a synthetic, long-acting dual agonist targeting both the GLP-1 receptor and the Glucagon receptor with an equimolar (1:1) potency ratio, formulated with a site-specific lipid diacid chain.
How it works: GLP-1 activation delivers glycemic stability and central satiety suppression, while concurrent glucagon receptor activation stimulates direct mitochondrial hepatic fat burning (beta-oxidation) and increased resting metabolic rate.
Why researchers study it: Researched in Phase 2 trials (MOMENTUM study) for metabolic dysfunction-associated steatohepatitis (MASH) and profound reduction of hepatic liver fat (over 75% relative reduction).




