Laboratory Reference Grade Compounds

Orforglipron (12mg Research Vial)

RUO In-VitroLyophilized Powder≥99% Reference Standard
Protocol SOP↓
₱3,600.00
Out of stock
Net Content12MG
InclusionVial + BAC Water
Volume Discounts:Up to 20% OFF
1
SOPReconstitution Telemetry (12MG)
Diluent:mL
Concentration12.00 mg/mLin 1.0mL BAC
Standard Dose3.0 mg – 12.0 mg Daily Analytical WindowSyringe: 50.0 units (0.50 mL)
Scale (1 Unit)120 mcgper 0.01 mL (U-100)
✓ Includes 10mL Bacteriostatic Water USPMonograph SOP →
Orforglipron (12mg Research Vial)12MG · Vial + BAC Water
₱3,600.00
1
Technical Specification & Protocol Dossier

Analytical Standards & Laboratory Handling

Verified laboratory protocols, reconstitution parameters, and handling guidelines.

P

Pharmacological Profile & Mechanism of Action

Research Monograph

What it is: Orforglipron (LY3502970) is a pioneering non-peptide small-molecule agonist of the GLP-1 receptor, engineered to achieve high oral bioavailability without requiring absorption enhancers.

How it works: Orforglipron binds to the transmembrane domain of the GLP-1 receptor, allosterically inducing downstream cAMP accumulation and glucose-dependent insulin secretion while profoundly suppressing appetite.

Why researchers study it: Researched in Phase 3 clinical trials (ACHIEVE program) for oral efficacy rivaling injectable peptide incretins, achieving significant reductions in HbA1c and body weight.

Compound & Molecular Specifications

Certificate of Analysis Standards
Target CategoryMetabolic Signaling & Incretins
Intended ApplicationLaboratory & In-Vitro Research Only (RUO)
Physical StateLyophilized Solid Powder
CAS Registry Number2212020-52-3
PubChem CID155196440↗
Molecular Weight766.8 g/mol
Purity Specification≥99.0% (HPLC-grade)
Net Content Options12MG
Inclusion PackagesVial Only, Vial + BAC Water, Analytical Lab Set
Peptide Sequence / FormulaC42H44F2N6O6