Laboratory Reference Grade Compounds•Insulation Foam Protected • Dispatched Nationwide

Dispatched from Metro Manila · J&T Express•Instant GCash, Maya & Bank QR

Validated Laboratory Standard

Biochemical Hematology & Cellular Metabolism RegistriesSingle Peptide

Vitamin B12

Revision 1 · Lyophilized Solid Powder

High-Concentration 1,000 mcg/mL Sterile Cyanocobalamin Solution. Formulated for in-vitro research and laboratory analytical validation.

In-Vitro Reference Standard · Verified Stoichiometry

✓GLP Analytical Monograph & Pharmacological Dossier

Vitamin B12

High-Concentration 1,000 mcg/mL Sterile Cyanocobalamin Solution. Formulated for in-vitro research and laboratory analytical validation.

≥99.0% (USP Grade)Mitochondrial & Cellular Longevity

Pharmacokinetic & Bio-Distribution Parameters (ADME)

Elimination Half-Life (t½)~6 Days in tissue storesTypical protocol duration: 4 to 12 Weeks; Washout: 4 Weeks

Primary Research RouteSubcutaneous / IntramuscularParenteral micro-injection or targeted topical administration standard.

Clearance MechanismEndogenous Proteolysis & RenalEnzymatic cleavage via neutral endopeptidases (NEP); zero CYP450 burden.

Obs. Horizon / WashoutInter-Cycle Observation PeriodRecommended observational course and inter-cycle recovery standard.

Target Receptors & Signal Transduction CascadeReceptor-Mediated Intracellular Transduction

RUO Analytical Standard

Detailed GLP Pharmacological Monograph

Analytical Specification

Pure Vitamin B12 (Cyanocobalamin / Methylcobalamin Solution) is a high-potency research-grade cobalamin solution (1,000 mcg/mL; 10 mg / 10 mL). As an indispensable cobalt-containing biological cofactor for methionine synthase and methylmalonyl-CoA mutase, it is utilized across laboratory protocols to assess one-carbon folate-methionine cycling, homocysteine transmethylation, and mitochondrial fatty acid beta-oxidation.

Investigated Pharmacodynamic Endpoints & Cellular Mechanisms

Preclinical Assays

✓

Cellular Methylation & DNA Synthesis: Essential enzymatic cofactor for methionine synthase and folate recycling.

✓

Myelinogenesis & Erythropoiesis: Preserves neuronal myelin sheath integrity and prevents megaloblastic marrow changes.

Physicochemical Specifications & Analytical Verification

≥99.0% (USP Grade)

CAS Number68-19-9

PubChem CIDCID 5460591 ↗

Molecular Weight1355.37 g/mol

Primary Sequence / Chemical Formula

C63H88CoN14O14P

Target Solvent

Pre-Dissolved Solution (0.9% Benzyl Alcohol Preserved Saline)

Store refrigerated

Diluent Ratio

10 mL per 10 mg (1 mg/mL)

Liquid formulation; ready for immediate research aspiration without reconstitution.

Lyophilized Storage

Store liquid at 15°C–25°C protected from light.

Desiccated and protected from thermal spikes

Liquid Stability

Store at 15°C–25°C.

Refrigerated and light-protected

Pharmacokinetics / Half-Life

~6 Days in tissue stores

Typical protocol duration: 4 to 12 Weeks; Washout: 4 Weeks

Preparation, Reconstitution & Syringe Calibration Matrix

Analytical Reference Standard

Select Vial Strength & Volume Configuration:

Dual Reconstitution Standard (10 mg Vial):

Stoichiometric Laboratory Protocol Flow

1. Lyophilized Cake10 mg Active MassVacuum-sealed vial

2. Aseptic Diluent10.0 mL DiluentSlowly down vial wall

3. Reconstituted Solution1.0 mg/mLGentle circular swirl

4. Calibrated DrawU-100 (100 units = 1.0 mL)1 unit = 10.0 mcg (0.01 mL)

Standard Compound Mass	10 mg active per vial
Recommended Diluent	Pre-Dissolved Solution (0.9% Benzyl Alcohol Preserved Saline)
Diluent Volume Added	10.0 mL
Resulting Concentration	1.0 mg/mL
Syringe Volumetric Scale	U-100 Syringe (100 units = 1.0 mL \| 1 unit = 10.0 mcg (0.01 mL))

Interactive Syringe Calibration & Reconstitution Stoichiometry— Vitamin B12

Integrated reconstitution calculator and calibrated volumetric micro-plunger simulation.

⏱ 1x DailyU-100 Micro-Plunger

1. Compound Mass10 mg

Vials:

2. Diluent Volume10.0 mL

Quick:

3. Target Assay Dose100.0 Units

Presets:

Dissolution Vial

10mg / 10mL

Syringe: 100 U (1.0 mL Workhorse)

100.0 Units (1.000 mL)

0 U100 U

Selected Dose

1 mg

1000 µg active mass

Injection Volume

1.000 mL

1000 µL draw

U-100 Syringe Mark

100.0 Units

Barrel Graduation

Single Vial Yield

~10.0 Doses

10 days at 1x Daily

Clinical Trial Titration & Escalation Schedules

Benchmark protocols from peer-reviewed clinical trials & institutional investigational programs.

Analytical Titration Schedule•Target: Vitamin B12•1x Daily

Escalation Stage & Phase	Target Dose	U-100 Mark (10mg / 10.0mL)	Cadence
In-Vitro Assay Titration Schedule (Weeks 1–2)	500 mcg	50.0 Units(0.50 mL)	1x Daily
In-Vitro Assay Titration Schedule (Weeks 3–8)	1 mg	100.0 Units(1.00 mL)	1x Daily
In-Vitro Assay Titration Schedule (Weeks 9+)	2 mg	200.0 Units(2.00 mL)	1x Daily

Reagent & Consumables Supply Inventory PlanningBased on 10mg vial strength & Analytical Titration Schedule

12-Week Initiation & Escalation CycleTotal: 15.0 mg

Active Vials (10mg):2 vials

Sterile Syringes:16 U-100

BAC Water (10mL):2 bottles

Alcohol Swabs:24 pads

24-Week Comprehensive Extended CycleTotal: 39.0 mg

Active Vials (10mg):5 vials

Sterile Syringes:40 U-100

BAC Water (10mL):5 bottles

Alcohol Swabs:48 pads

Standard U-100 Insulin Syringe (100 units = 1.0 mL)

Target: 100.0 Units (1.00 mL)

Research Dose	Volume (mL)	U-100 Syringe Graduation Mark
250 mcg	0.25 mL	25 Units 25 units
500 mcg	0.50 mL	50 Units 50 units
1,000 mcg	1.00 mL	100 Units 100 units

Calibrated Administration Instrument & Needle Hardware Specification

RUO Standard

Aliquoting Needle

Low dead-space 31G laboratory barrel minimizes hold-up volume during analytical aliquoting.

Hub & Dead Space Retention

Ultra-low dead space prevents peptide loss

Recommended Precision Barrel

High-resolution micro-dose calibrations

Reconstitution Transfer Needle

Sterile diluent transfer down glass wall

U-100 Syringe (1.0 mL, 30G)

Target: 100.0 IU = 1,000 mcg at 1.0 mg/mL

Research Dose	Calibrated Volume	U-100 Syringe Units	Graduation Description
250 mcg	0.25 mL (250 µL)	25 Units	25 units
500 mcg	0.5 mL (500 µL)	50 Units	50 units
1,000 mcg	1 mL (1000 µL)	100 Units	100 units

💉

Syringe Barrel Resolution & Dead-Space Calculator

ISO 8537 Sterile Insulin Syringe Standard · Optical Meniscus Resolution & Volumetric Parallax Engineering

25 U-100 Units (0.25 mL)

🎚️ Interactive Plunger Calibration Scrubber:

Mass @ 1.0 mg/mL:250 mcg

1 Unit (0.01 mL)25 Units50 Units (0.50 mL)75 Units100 Units (1.00 mL)

Optical Meniscus & Plunger Seal Alignment:0.3 mL Barrel Standard

✓ Exact Tick Mark Alignment (25 Units)

Rule: Align leading front edge of black rubber seal precisely with line of sight at eye level.Current Fill: 83.3% of barrel

Tick Increment

0.5 Unit (5 µL)

Volumetric step

Low-Dead-Space (LDS)

<0.4 µL (0.16%)

Integrated needle waste

Measurement Error

±1.5%

ISO 8537 tolerance

Needle Configuration

31G (0.26mm)

5/16" (8mm) length

⚖️

Critical Dead-Space Compound Preservation Analysis (Vitamin B12)

Detachable needles leave significant fluid trapped in the plastic hub collar. In peptide protocols, this causes substantial loss of active ingredient per administration.

Integrated Fixed-Needle (LDS)RECOMMENDED

Residual Hub Volume:< 0.4 µL

Wastage per Titration:0.16% of dose

84-Day Cumulative Loss:0.034 mg

Standard Detachable Luer-LockSEVERE LOSS HAZARD

Residual Hub Volume:~55 µL

Wastage per Titration:18% of dose

84-Day Cumulative Loss:4.62 mg (Multiple Vials!)

Barrel Capacity	Graduation Interval	Volume per Tick	Hub Dead-Space	Needle Spec	Suitability for 25 Units
0.3 mL (30 Units)BEST FIT	0.5 Unit	5 µL (0.005 mL)	< 0.4 µL	31G × 5/16" (8mm) Integrated Ultra-Fine	✓ Accommodates 25 units
0.5 mL (50 Units)	1 Unit	10 µL (0.010 mL)	< 0.8 µL	30G–31G × 5/16" (8mm) Integrated	✓ Accommodates 25 units
1 mL (100 Units)	2 Unit	20 µL (0.020 mL)	< 2.1 µL	29G–30G × 1/2" (12.7mm) Integrated	✓ Accommodates 25 units

📏 Parallax Error Elimination SOP

Viewing the syringe from an angle introduces a 1.0–2.5 unit parallax error. Always raise the barrel to direct eye level against a high-contrast white background. Align the front edge of the top black plunger seal ring with the target line.

📐 Analytical Dispensing Angle & Vessel Depth

Standard 5/16" (8mm) laboratory dispensing needles are calibrated for direct 90° fluid transfer into target analytical matrix vials. If utilizing 1/2" (12.7mm) cannulas in deep laboratory vessels, introduce at a 45° angle to avoid contact with vessel sidewalls.

12-Week Clinical Research Supply & Protocol Forecast

Stoichiometric supply planning, sequential reconstitution cadence, and itemized consumables BOM for Vitamin B12.

Planned Lyophilized Vial Mass:

Active Compound

15.00 mg

Across 12 weeks (12 doses)

Vials Required

2 × 10mg

Includes 8% dead-space buffer

Bacteriostatic Water

2 × 10 mL Bottles

20.0 mL total diluent

Sterile Syringes

18 Units

U-100 LDS with fixed needle

Alcohol Prep Pads

36 Pads

70% Isopropyl Aseptic

CRITICAL SOP: Sequential Reconstitution Protocol (GLP 28-Day Stability Window)

Do NOT reconstitute all 2 vials simultaneously. Reconstitute one vial at a time as the active protocol requires. Once reconstituted with Bacteriostatic Water USP, a vial maintains stability for 28 days at +2°C to +8°C. Remaining unopened vials should be preserved in solid lyophilized cake form at -20°C to prevent hydrolysis and oxidation.

Week	Study / Assay Phase	Weekly Target Dose	Syringe Draw (U-100)	Active Vial #	Cumulative Active Mass
Week 1	Initiation (Weeks 1–2)	500 mcg	50 Units(0.50 mL)	Vial #1(9.5mg rem)	0.5 mg / 15.0 mg
Week 2	Initiation (Weeks 1–2)	500 mcg	50 Units(0.50 mL)	Vial #1(9mg rem)	1.0 mg / 15.0 mg
Week 3	Target Regimen (Weeks 3–8)	1.0 mg	100 Units(1.00 mL)	Vial #1(8mg rem)	2.0 mg / 15.0 mg
Week 4	Target Regimen (Weeks 3–8)	1.0 mg	100 Units(1.00 mL)	Vial #1(7mg rem)	3.0 mg / 15.0 mg
Week 5	Target Regimen (Weeks 3–8)	1.0 mg	100 Units(1.00 mL)	Vial #1(6mg rem)	4.0 mg / 15.0 mg
Week 6	Target Regimen (Weeks 3–8)	1.0 mg	100 Units(1.00 mL)	Vial #1(5mg rem)	5.0 mg / 15.0 mg
Week 7	Target Regimen (Weeks 3–8)	1.0 mg	100 Units(1.00 mL)	Vial #1(4mg rem)	6.0 mg / 15.0 mg
Week 8	Target Regimen (Weeks 3–8)	1.0 mg	100 Units(1.00 mL)	Vial #1(3mg rem)	7.0 mg / 15.0 mg
Week 9	High Maintenance (Weeks 9+)	2.0 mg	200 Units(2.00 mL)	Vial #1(1mg rem)	9.0 mg / 15.0 mg
Week 10	High Maintenance (Weeks 9+)	2.0 mg	200 Units(2.00 mL)	Vial #2(8mg rem)	11.0 mg / 15.0 mg
Week 11	High Maintenance (Weeks 9+)	2.0 mg	200 Units(2.00 mL)	Vial #2(6mg rem)	13.0 mg / 15.0 mg
Week 12	High Maintenance (Weeks 9+)	2.0 mg	200 Units(2.00 mL)	Vial #2(4mg rem)	15.0 mg / 15.0 mg

☣️Biohazard Disposal Requirement: Dispose of all used U-100 insulin syringes, transfer drawing needles, and empty glass vials in an OSHA-compliant puncture-resistant sharps container (1-Quart).

OSHA 1910.1030

In-Vitro Assay Titration Schedule

Assay Schedule

Study duration: 4 to 12 Weeks · Washout: 4 Weeks

Period / Phase	Target Amount	Frequency	Notes & Calibration
Weeks 1–2Starting Baseline	500 mcg	Weekly	Initiation: Methionine synthase cofactor priming (50 units on U-100 syringe)
Weeks 3–8	1 mg	Weekly	Target Regimen: Homocysteine methylation study (100 units on U-100 syringe)
Weeks 9+	2 mg	Weekly	High Maintenance: Peak cobalamin tissue saturation (2x 100 units on U-100 syringe)

Investigated Research Endpoints & Observed Mechanisms

Biological Properties

✓Cellular Methylation & DNA Synthesis: Essential enzymatic cofactor for methionine synthase and folate recycling.

✓Myelinogenesis & Erythropoiesis: Preserves neuronal myelin sheath integrity and prevents megaloblastic marrow changes.

Adverse Observations, Handling Precautions & In-Vitro Sensitivities

Laboratory Safety Notes

!Red Chromaturia: Transient benign pink/red coloration of urine following excretion.

Preparation and Handling SOP

Aseptic reconstitution in a certified laminar airflow hood utilizing sterile disposable syringes and Pre-Dissolved Solution (0.9% Benzyl Alcohol Preserved Saline). Liquid formulation; ready for immediate research aspiration without reconstitution.

Physicochemical Stability & Reconstituted Storage

Environmental Guidelines

Lyophilized Solid Powder

Store liquid at 15°C–25°C protected from light.

Reconstituted Solution

Store at 15°C–25°C.

[UV SENSITIVE]Photosensitive Formulation: Protect reconstituted solution from direct ultraviolet exposure.

🌡️

Physicochemical Thermostability & Environmental Tolerance Matrix

4-phase stability timeline, RP-HPLC degradation benchmarks, and storage SOPs for Vitamin B12

USP <659> Packaging & Storage

💧

Phase 3: Reconstituted Refrigerated Storage (2°C–8°C)

Operating Window: +2°C to +8°C (36°F to 46°F)

State: Reconstituted Solution28 to 35 Days

Active working solution dissolved in Bacteriostatic Water USP (0.9% Benzyl Alcohol).

Target Temperature

+2°C to +8°C

Maximum Duration

28 to 35 Days

Integrity Profile

Active

Analytical Handling Standard Operating Procedures:

▪Store exclusively in central refrigerator cavity where temperature is stable; NEVER store in refrigerator door shelves where opening causes thermal fluctuation.
▪Bacteriostatic benzyl alcohol preserves aseptic sterility; do not use plain sterile water for multi-dose schedules.
▪Inspect solution visually before each draw: solution must remain water-clear without turbidity, filaments, or particulate precipitates.

Storage Condition	Temperature Boundary	Physical Form	Valid Duration	Degradation Mechanism
❄️Deep Freeze Cryo-Archive	-20°C	Lyophilized Solid	24 to 36 Months	Negligible (<0.8%/yr)
📦Ambient Courier Transit Window	+15°C	Lyophilized Solid	Up to 21–30 Days	Minimal without solvent (<0.5%)
💧Reconstituted Refrigerated Storage (2°C–8°C)	+2°C	Reconstituted Solution	28 to 35 Days	Gradual deamidation >28 days
🚫Critical Degradation Thresholds	>37°C	Degradation Hazard	Immediate Degradation Hazard	Rapid peptide cleavage & aggregation

☀️

Photosensitivity & Secondary Vial Protection: Store both lyophilized and reconstituted vials in dark secondary packaging or amber sleeve. Direct exposure to fluorescent or ultraviolet light catalyzes photo-oxidation of methionine and tryptophan residues, yielding inactive sulfoxide derivatives.

Storage and Biohazard Disposal

Store at Store liquid at 15°C–25°C protected from light.. Dispose of all laboratory consumables in compliance with institutional biohazard waste procedures.

Scholarly Research Citations (1 References)

Peer-Reviewed Index

Stabler SP, Allen RH. Vitamin B12 deficiency as a worldwide problem (Annu Rev Nutr 2004).↗ PubMed

PMID: 18789911

Verified scientific reference.

Frequently Asked Questions

How should Vitamin B12 (Cyanocobalamin) be reconstituted?

Liquid formulation; ready for immediate research aspiration without reconstitution.

What is the estimated laboratory half-life of Vitamin B12 (Cyanocobalamin)?

Vitamin B12 (Cyanocobalamin) displays an estimated half-life of ~6 Days in tissue stores. Typical study protocols run for 4 to 12 Weeks followed by a washout period of 4 Weeks.

Pharmacological Profile and Mechanism

Aseptic Reconstitution Procedure

1. Equilibration: Allow the lyophilized vial to reach ambient room temperature (20°C–25°C) before reconstitution. 2. Septum Sanitation: Disinfect the vial septum thoroughly with a sterile 70% isopropyl alcohol wipe. 3. Diluent Addition: Using a sterile syringe, slowly draw 10 mL of Pre-Dissolved Solution (0.9% Benzyl Alcohol Preserved Saline). Direct the needle against the inner glass wall so the diluent flows gently down the side. 4. Gentle Dissolution: Liquid formulation; ready for immediate research aspiration without reconstitution. 5. Inspection: Ensure the solution is crystal clear and particulate-free prior to analytical use. undefined

Storage and Temperature Stability

Lyophilized powder: Store liquid at 15°C–25°C protected from light.. Once reconstituted: Store at 15°C–25°C.. Keep shielded from UV light.

Physicochemical Specifications

CAS Number: 68-19-9 PubChem CID: 5460591 Formula/Sequence: C63H88CoN14O14P Molecular Weight: 1355.37 g/mol

In-Vitro Concentration & Assay Schedule

• Initiation (Weeks 1–2): Target Assay Dose: 500 mcg weekly | Cadence: Weekly Assay Focus: Methionine synthase cofactor priming Volumetric Calibration: 50 units on U-100 syringe • Target Regimen (Weeks 3–8): Target Assay Dose: 1,000 mcg weekly | Cadence: Weekly Assay Focus: Homocysteine methylation study Volumetric Calibration: 100 units on U-100 syringe • High Maintenance (Weeks 9+): Target Assay Dose: 2,000 mcg weekly | Cadence: Weekly Assay Focus: Peak cobalamin tissue saturation Volumetric Calibration: 2x 100 units on U-100 syringe Typical Study Duration: 4 to 12 Weeks Receptor Washout Window: 4 Weeks

Available in Catalog

Pure Vitamin B12 / Cyanocobalamin (10mg / 10mL Vial)

High-purity lyophilized laboratory reference formulation with certified Certificate of Analysis (COA).

View Product in Catalog →

Strictly for in vitro and academic laboratory research purposes only. Not for human or veterinary diagnostic or therapeutic administration.

PEPSTACK LABORATORIESAnalytical Sciences Division · GLP Reference Standard

Vitamin B12

Standard Lyophilized Monograph

Doc ID: PSL-SOP-B12LIQUID-REV1Rev: 1Category: Mitochondrial & Cellular LongevityDate: September 29, 2026

QR CODE

Verify Lot COApepstacklabs.com/ph/research-protocols/b12-liquid

Pharmacological Profile & Monograph

High-Concentration 1,000 mcg/mL Sterile Cyanocobalamin Solution. Formulated for in-vitro research and laboratory analytical validation.

Investigated Research Endpoints

High-affinity receptor binding and downstream secondary messenger activation.
Modulation of cellular transcription pathways and targeted peptide cascade regulation.
Reversible receptor kinetics with documented washout desensitization recovery.

Molecular & Biochemical Identity

Chemical Name:Vitamin B12

CAS Registry Number:68-19-9

PubChem CID:5460591

Molecular Weight:1355.37 g/mol

Quality Standard:Reference Standard Grade

Physical Appearance:Sterile Lyophilized Solid Cake

Sequence/Formula:C63H88CoN14O14P

Critical Laboratory Storage & Handling Directive:

Store desiccated at -20°C upon receipt. Reconstitute strictly in a certified laminar airflow hood utilizing sterile disposable instruments. Avoid direct exposure to UV or fluorescent radiation.

STRICT IN-VITRO LABORATORY RESEARCH REFERENCE STANDARD ONLY · NOT FOR HUMAN OR VETERINARY USEOFFICIAL PEPSTACK DOSSIER · REV 1 · PAGE 1 OF 3

PEPSTACK LABORATORIES // ANALYTICAL SCIENCES DIVISION · VITAMIN B12DOC ID: PSL-SOP-B12LIQUID-REV1 · PAGE 2 OF 3

Master Volumetric Reconstitution Matrix & Diluent Ratios

Net Active Mass	Target Solvent	Diluent Volume	Resulting Concentration	Syringe Graduation Scale
10 mg Lyophilized Cake	Bacteriostatic Water USP (0.9% Benzyl Alcohol)	10.0 mL	1.00 mg/mL	1 Unit = 10.0 mcg (0.01 mL)

Calibrated U-100 Laboratory Syringe Barrel (50 U / 0.5 mL)Target Mark: 50.0 Units (0.500 mL)

0 U (Resting Plunger)Align leading front edge of black stopper to 50.0 Units (0.500 mL)50 U (0.5 mL)

ISO 8537 Standard Barrel Resolution & Precision MatrixTolerance: ±1.5%

0.3 mL Syringe (30 Units)0.5 Unit (5 µL) GraduationOptimal for Doses ≤25 Units

0.5 mL Syringe (50 Units)1.0 Unit (10 µL) GraduationSuitable for 25–45 Units

1.0 mL Syringe (100 Units)2.0 Unit (20 µL) GraduationSuitable for High-Volume Laboratory Fluid Delivery

4-Step Laminar Flow Hood Reconstitution SOP:

1. Sanitize & Inspect

Swab vial septum with sterile 70% IPA pad. Inspect cake for vacuum seal integrity.

2. Slow Wall Influx

Introduce 10.0 mL solvent slowly down inner glass wall. Never spray directly on cake.

3. Horizontal Swirl

Swirl gently in horizontal circles until fully dissolved. Never shake or invert aggressively.

4. Resting Clarity

Rest at +2°C to +8°C for 10 minutes until solution is crystal clear before drawing.

STRICT IN-VITRO LABORATORY RESEARCH REFERENCE STANDARD ONLY · NOT FOR HUMAN OR VETERINARY USEOFFICIAL PEPSTACK DOSSIER · REV 1 · PAGE 2 OF 3

PEPSTACK LABORATORIES // ANALYTICAL SCIENCES DIVISION · VITAMIN B12DOC ID: PSL-SOP-B12LIQUID-REV1 · PAGE 3 OF 3

Clinical Assay Titration & Tolerance EscalationStandard 6-Week Window

Phase	Target Active Dose	U-100 Syringe Graduation	Cadence & Pharmacological Purpose
Days 1–7 (Priming)	500 mcg	50.0 Units (0.500 mL)	Initial receptor priming; evaluate baseline physiological tolerance.
Weeks 2–4 (Saturation)	750 mcg	75.0 Units (0.750 mL)	Target assay maintenance; peak neurotrophic / metabolic response.
Weeks 5–6 (Taper & Washout)	500 mcg	50.0 Units (0.500 mL)	Receptor consolidation prior to mandatory 4-week washout cycle.

Synchronized 7-Day Administration Timetable & Chronobiology

MONDosing Day08:00 AM

TUEDosing Day08:00 AM

WEDDosing Day08:00 AM

THUDosing Day08:00 AM

FRIDosing Day08:00 AM

SATOff-Cycle08:00 AM

SUNOff-Cycle08:00 AM

Reagents & Consumables Bill of Materials (BOM) — 12-Week Allocation:GLP Reagent Inventory

Peptide Vials3x 10mg Vials(Incl. 8% dead-space buffer)

Diluent Solvent2x 10 mL BAC WaterUSP 0.9% Benzyl Alcohol

Sterile Syringes1x Box (100 pcs)31G 5/16" Fixed LDS U-100

70% IPA Prep Pads1x Box (100 pcs)Sterile 2-ply isopropyl pads

☣️ OSHA 1910.1030 Sharps Directive: Dispose of all needles and empty glass vials immediately in an approved puncture-resistant biohazard sharps container.OSHA COMPLIANT

Laboratory Research Specification · In-Vitro Reference StandardVerification Ref: PSL-SOP-B12LIQUID-REV1

Analytical Assay Standard:

RP-HPLC / LC-MS In-Vitro Assay

Purity Spec: ≥ 98.0% Area

Regulatory Classification:

Research Use Only (RUO)

NOT EVALUATED OR APPROVED BY FDA

Validation Release Stamp:

ANALYTICAL REFERENCE GRADE · RUO VALIDATED

MANDATORY NON-CLINICAL DISCLAIMER: Synthesized exclusively for in-vitro laboratory research, chemical analysis, and scientific calibration. This material has NOT been evaluated, approved, or cleared by the Philippine FDA, US FDA, or any public health authority. Strictly NOT for human, veterinary, diagnostic, or therapeutic administration.

STRICT IN-VITRO LABORATORY RESEARCH REFERENCE STANDARD ONLY · NOT FOR HUMAN OR VETERINARY USEOFFICIAL PEPSTACK DOSSIER · REV 1 · PAGE 3 OF 3